180 projects (people) won the 2021 Guangdong Science and Technology Award
Yangcheng Evening News All-Media Reporter Li Gang
On the 15th, the Provincial Science and Technology Innovation Conference was held in Guangzhou, and the 2021 Guangdong Science and Technology Award was awarded, with a total of 180 projects (people) winning awards. Among them, the three major achievements of “Construction of China’s Food Microbial Safety Science Database and Its Innovative Application”, “National Major Scientific Infrastructure Project for Split Neutron Sources”, and “Key Technology Research and Development and Industrialization of High-end Pure Electric Passenger Vehicles” won the Science and Technology Progress Award.
“Construction and innovative application of China’s food microbial safety science database”
Reduced the microbial pollution rate by more than 90%, greatly ensuring the “tips of tongue safety”
It is understood that the “Construction and innovative application of China’s food microbial safety science database” project was completed by the Institute of Microbiology, Guangdong Academy of Sciences and other institutions. The project results have effectively solved the important scientific and technological problems of “bottleneck” in my country’s food microbial safety, significantly improved prevention and control efficiency, covered my country’s main food industry chain, and reduced the microbial pollution rate by more than 90%, greatly improving the level of food safety guarantee.
Wu Qingping, an academician of the Chinese Academy of Engineering and honorary director of the Institute of Microbiology, Guangdong Academy of Sciences, introduced that among the factors affecting food safety, microorganisms are one of the most important factors, and more than 60% of food poisoning are caused by deadly microorganisms. Therefore, its team has been committed to building a large database of food microbial safety science for the past decade. After nationwide sampling and comprehensive analysis, the team has built 6 databases: risk identification database, strain resource database, distribution database, genome databaseKomiks, barcode fingerprint database, and traceability tracking database. Wu Qingping said that through this scientific database, the overall risk level of food microbial safety in China can be presented, as well as what are the pathogenic microorganisms that are found to be mainly contaminated, and then further study how food hazards are formed and understand their mechanisms. He revealed that the risk identification database of the single database of this result is the largest in the world, with the largest number of bacterial species and sequencing. More than 20,000 experimental pathogenic microorganisms have been sequenced, and nearly 200 new detection targets have been dug out, successfully achieving full coverage of experimental pathogenic bacteria detection.
“National Major Scientific and Technological Infrastructure of Spallation Neutron Sources”
The first national large scientific facility in the Pearl River Delta, a “weapon” for scientific research and intelligent manufacturing
Chen Hesheng, an academician of the Chinese Academy of Sciences and commander-in-chief of the Spallation Neutron Source Engineering Command, introduced that spallation neutron sources are like “super microscopes” and are the principle of studying the microstructure of material materials.href=”https://comicmov.com/”>Cinema wants the probe. In January 2006, the Chinese Academy of Sciences launched a prefabricated research project for spalling neutron sources. In the same year, the project was chosen to settle in Dalang Town, Dongguan. By October 2011, the China Spallation Neutron Source, with a total investment of approximately RMB 2.3 billion, was laid in Dongguan, ending the history of no national large scientific installations in the Pearl River Delta region.
In the autumn of 2017, China’s spall neutron sources successfully obtained a neutron beam that was fully in line with expectations for the first time, and the debugging speed was far higher than that of foreign spall neutron sources. In March 2018, China’s spall neutron source passed the process testing and appraisal organized by the Chinese Academy of Sciences. All Komiks performance indicators met or were better than the acceptance indicators. The engineering construction tasks were completed according to the indicators, according to the construction period and with high quality. The technology and comprehensive performance entered the list of similar devices in the international category. The project has officially passed the national acceptance, filling the gap in the field of pulse neutron application in China, and is open to domestic and foreign users.
As of now, spalling neutron sources have completed about 700 user experimental projects, carried out major innovative research in many fields, and carried out residual stress and service performance detection of large-scale engineering components such as deep-sea submersibles, providing a key technical platform for the research and development of many high-performance structural materials urgently needed by the country.
China’s spall neutron source is the first major scientific and technological infrastructure in the Guangdong-Hong Kong-Macao Greater Bay Area. The most direct benefit of its construction is to bring research to scientific researchers, especially to provide unprecedented convenience for Hong Kong and Macao scientists to use spall neutron sources. At the same time, the Greater Bay Area is a highland of advanced manufacturing in the country and has an urgent need for materials science research. The layout of spalling neutron sources in Dongguan is of great significance.
Chen Hesheng also revealed that the second phase of the Spallation Neutron Source project was officially included in the “14th Five-Year Plan” for the construction of major scientific and technological infrastructure in the first half of 2021. All preliminary preparations have been approved by relevant departments and are expected to officially start this year. The number of spectrometers in the future will increase to 20, covering all research fields of users. The power of accelerator target shooting and target stations will be increased from 100 kilowatts to 500 kilowatts. The equipment research capabilities will be greatly improved, which can greatly improve the accuracy and speed of experiments, measure smaller samples, study faster dynamic processes, meet the needs of more users at home and abroad, and provide more advanced research for cutting-edge scientific research, major national needs and national economic development.Research the platform and make more contributions to achieving high-level scientific and technological self-reliance.
“Research and development and industrialization of key technologies for high-end pure electric passenger cars”
Support Guangdong’s leading position in the development of new energy vehicles nationwide
Cinema
According to Lian Yubo, vice president and senior engineer of BYD Automobile Co., Ltd., the project “Research and development and industrialization of key technologies for high-end pure electric passenger cars” has achieved three major technological breakthroughs, including the creation of a “sandwich” structure with high safety module-free blade battery system href=”https://comicmov.com/”>Cinema system, creating high-power, low-loss SiC module controller design and manufacturing technology, and creating a high-voltage deep integrated architecture for charging and driving, and overcoming the pain points such as thermal runaway from power batteries, peak voltage suppression caused by SiC fast switching, and difficulty in quickly replenishing energy in low-voltage charging piles. Key indicators such as structural power battery system volume energy density, comprehensive efficiency of SiC drive assembly, and maximum charging power are all superior to Tesla.
According to reports, the project authorized 79 invention patents and 43 utility model patents, leading the formulation of 14 national standards, including my country’s first national standard for mandatory electric vehicle safety, and leading the formulation of the world’s first electric vehicle safety technical regulations on behalf of China. The project results were identified by the expert group: “The overall level is at the international advanced level, and the integrated architecture technology of blade power battery and charging and driving is at the international leading level.”
The project breaks through the difficulties of synergistic improvement of safety, endurance and power of high-end pure electric vehicles, and creates a series of high-end pure electric models, with leading sales in the independent model. At the same time, it will achieve technical output and product supporting to foreign first-class brands such as Toyota. The direct economic benefits exceeded 100 billion yuan in the past three years, strongly supporting Guangdong’s leading position in the field of new energy vehicles in the national field of new energy vehicles, and helping Guangdong build a world-class new energy vehicle industry highland.
Some projects of the first prize of the Natural Science Award
Research on the stratigraphics of the Loess Plateau: Refreshing the cognition of the origin and migration history of ancient humans
This time, the “Year of the Loess Stratigraphics and New Discoveries of the Paleoenvironment and Early Human Evolution in the Loess Plateau” project, which won the first prize of the Natural Science Award, was led by the Guangzhou Institute of Geochemistry, Chinese Academy of Sciences. The results are sufficient to change the understanding of the traditional migration and diffusion patterns of ancient humans.
It is understood that this project belongs to the basic research of Quaternary geology. The origin and evolution of human beings are major scientific issues in the study of Quaternary and “paleoglobal changes”, and are currentlyHigh-resolution environmental evolution sequences of paleozoos, ancient plants and even archaeobacteria have been established, but the research on the “high-resolution environmental evolution sequence” of ancient humans is very rare. The biggest difficulty is that a good sedimentary sequence and activity place has not been found.
Zhuyu, a researcher at the Guangzhou Institute of Geochemistry, Chinese Academy of Sciences and the first completed project, introduced that Lantian, Shaanxi in the southern part of the Loess Plateau, has 37 loess-paleosoil strata sequences, recording the 37 ice-interglacial climatic cyclones in the Quaternary period, and several ancient human fossils and stone sites have been discovered. From 2001 to 2018, Zhu Zhaoyu took the lead in joining a research team composed of more than ten scientific research and university scholars at home and abroad to conduct cross-cooperation surveys and research in the Lantian area, and accumulated thousands of first-hand data.
The research work independently discovered the ancient human stone tools in the loess layer 2.12 million years ago. Using a variety of technical methods and high-resolution paleomagnetic dating, the two most important paleomagnetic events – the Oduwee and Reunion positive polarity sub-phase, were detected, and the stone tools of the oldest loess strata, Komiks in Babaylan were 2.12 million years ago, 270,000 years earlier than the internationally recognized Demanisi stone tools (1.85 million years) in Georgia, which is 270,000 years earlier. This new discovery makes Lantian Shangchen Village one of the oldest human activity sites known outside Africa to date, rewriting the history of early human origins and migrations.
The study also re-determined the age of the skull of Gongwangling from 1.15 million years ago to 1.63 million years ago, making it the second oldest skull fossil known beyond Africa to date. It determined that Homo erectus had appeared in East Asia at least 1.6 million years ago, changing the understanding of the traditional ancient human migration and diffusion patterns.
In addition, the team independently discovered 23 Paleolithic layers from 450,000 to 21,000 years in Shangchen Village, Lantian, and used various paleoenvironmental indicators to reveal the evolutionary characteristics of the living environment of ancient humans on a long-term scale. This is a new discovery with long scale, multi-stage, and high frequency unique to the world that is known at present. It laid the foundation for making Lantian a global time mark and landmark, and at the same time opened a breakthrough in the weak links of “high-resolution evolutionary sequences of ancient humans and their living environment” in the study of “paleoglobal changes”.
The project results were awarded the national “Top Ten Progress in Chinese Science in 2018”, and are also the first author in Guangdong Province to dateThe only geological scientific achievement obtained by the leader, and was rated as the “most important discovery in the field of human evolution in the past decade (2010-2019).
Mesenchymal stem cell technology: providing new treatment strategies for difficult and serious diseases
The “Series of Research on Functional Characteristics, Treatment Mechanism and Clinical Transformation of Mesenchymal Stem Cells” project completed by Sun Yat-sen University’s Stem Cells and Regenerative Medicine Innovation Platform was won by the first prize of the Cinema Natural Science Award.
Xiang Peng, head of the innovation platform for stem cell and regenerative medicine at Sun Yat-sen University and the first person to complete the project, introduced that stem cell technology is currently the need for the treatment of major diseases. Regenerative medicine with stem cells as the core is expected to become the third disease treatment method after drug treatment and surgical treatment, providing new treatment strategies for major refractory diseases. After nearly 20 years of research, the research team has achieved a series of breakthrough results in the functional characteristics, therapeutic mechanism and clinical transformation of mesenchymal stem cells. Xiang Peng said that almost every organ and tissue in the body has mesenchymal stem cells (MSCs). Komiks not only has a wide range of sources, but is also easy to isolate and amplify. It can differentiate multiple times and participate in hematopoietic support, immune regulation, tissue damage repair, etc., and has a broad clinical application scenario. However, as of now, neither China nor the United States have approved any MSC product to be launched. The reason is that MSC clinical transformation still faces a series of bottlenecks that need to be solved urgently.
In response to the bottleneck, the project team has cooperated to solve scientific issues such as “Cinema to discover functional subgroups, reveal the treatment mechanism, and accurately select indications”, and has made important breakthroughs.
The team took bone marrow MSC as the entry point to deeply analyze the mode of action of MSC in different pathological microenvironments, revealing the multi-dimensional and multi-target immune regulation mechanism of MSC, and providing a scientific basis for the clinical accurate selection of MSC indications. On this basis, the team accurately selected indications and took the lead in clinical research on MSC treatment of transplant rejection diseases in the world, confirming that MSC is safe and effective in treating chronic graft-versus-host disease, and for the first time revealed that regulatory B cells are a key target for MSC treatment. Based on an in-depth understanding of MSCs, the team took the lead in formulating the first domestic group standard for “Human Mesenchymal Stem Cells” and the first domestic allogeneic human bone marrow M developed.SC injection has been approved by the National Medical Products Administration for drug clinical trials and is expected to achieve breakthrough treatment for major refractory diseases.
Data
The number of awards won by institutions in Guangzhou accounts for nearly 75% of the province
Yangcheng Evening News Reporter Li Gang reported: On the 15th, the Provincial Science and Technology Innovation Conference issued a list of winners of the 2021 Guangdong Science and Technology Awards. Among them, Guangzhou won 134 awards (persons), accounting for 74.4% of the total awards, ranking first in the province.
It is understood that from the perspective of reward level, Guangzhou won 1 special prize and 40 first prizes (accounting for 83.3% of the province). From the perspective of award categories, three foreigners including Martin Banwell, Marukoka, Marukoji, who cooperated with Guangdong University of Technology, and Badani, who cooperated with Guangzhou University of Technology, and Badani, who cooperated with Guangzhou University of Science and Technology, won the Science and Technology Cooperation Award (accounting for 3/4 of the province). Among the 134 award-winning projects (people), 111 items were completed and 23 items were participated by Guangzhou enterprises and institutions. Guangzhou’s award-winning projects continue to maintain the province’s leading advantage in terms of quantity and quality.
In addition, Guangzhou’s scientific and technological strength has won awards in key areas and achieved impressive results. Award-winning projects in strategic emerging industries such as biomedicine, electronic information, energy conservation and environmental protection, Komiks, new materials, high-end equipment manufacturing, etc. account for 79.4% of the total number of awards won in Guangzhou, among which the advantages of the biomedicine field are the most obvious. A total of 1 special prize, 13 first prizes, and 19 second prizes won, and Babaylan accounted for 21.3% of the total number of awards won in the city.
The award-winning projects also further highlight the collaborative innovation achievements of Guangzhou’s industry, academia and research. According to statistics, among the award-winning projects, there are 104 universities and research institutes in Guangzhou, including 77 projects jointly won by enterprises and 36 award-winning projects in Guangzhou, mainly distributed in biomedicine, energy conservation and environmental protection, agriculture and other fields.