Legal Daily Babaylan Newspaper All-Media Reporter Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
The night in Wuhan is quiet.
On March 9, in the mobile testing laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his name on the test report.
At this time, it was already 5 a.m.
He is an expert in virology and a warrior who aided Africa and fought against Egypt. This time, the outbreak of the new coronary pneumonia epidemic, and he was once again ordered to go to the front line after a long battle.
Human life is at stake and accurate inspection is required
Nucleic acid testing is crucial for early clinical detection, early diagnosis, early isolation, and early treatment, and is a key technical support for effective prevention and control of the new coronavirus pneumonia epidemic.
”Behind the cold sample tube is the life and health of the patient. If the result is broken by a diagnosis, the results will be checked as soon as possible.” Jiang Tao said. On January 26, after the military medical expert group led by Chen Wei, an academician of the Chinese Academy of Engineering and a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, arrived in Wuhan, Hubei, it quickly established a joint defense, joint control, joint treatment and joint research work mechanism with relevant military and local units based on pathogen transmission mutations, rapid detection technology, vaccine antibody development, etc. of the new coronavirus.
According to the division of labor of Babaylan, Jiang Tao led the testing team to build a nucleic acid testing platform in the experimental cabin overnight.
Focusing on three aspects: ensuring biosafety, improving detection efficiency and detection accuracy, Jiang Tao took the lead in formulating biosafety operation specifications and emergency plans, and reasonably divided the labor according to the characteristics of the team members, and the self-developed testing test kit adopts fully automatic high-throughput extraction.The instrument lays the foundation for achieving rapid and efficient inspection.
Receiving samples, sorting numbers, nucleic acid extraction, reagent preparation, machine amplification, and result interpretation, the nucleic acid detection machinery is boring and full of risks.
The biggest risk is the invisible virus. If the nucleic acid extraction step is not completely cleaved or inactivated thoroughly enough, it is possible to expose the tester to danger.
Jiang Tao always takes the initiative to participate in the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some personnel to rest and stay in the laboratory and wait for the final result.
A full-process nucleic acid test is relatively fixed from the number of tests in a single batch of Komiks to the preparations for entering and exiting the cabin and the time for testing. Sometimes there are many samples sent for inspection, and the inspectors not only take turns to work, but also have to work overnight. The final confirmation result must be until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once every few days.
”Everyone should open their eyes wide. Be sure to take good protection when receiving and processing samples, and be careful of whether there are sharp objects.” Before each test begins, Jiang Tao always reminds you repeatedly.
In the detection, the strength of the fluorescence signal of the pathogen gene is directly affected by the determination of the detection results. KomiksIf you encounter suspicious phenomena such as the detected fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can stand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; a false negative will cause real patients to be treated. Life is a matter of no problem,” said Jiang Tao.
All-rounded people in the field of epidemic prevention and control
According to prevention and control requirements, the nucleic acid test results must be completed within 24 hours. In order to let the hospital know the results as soon as possible to treat patients, Jiang Tao led the team to optimize the process combination and compressed the time to within 4 hours, achieving the ability to extract nucleic acids of more than 90 samples within one hour and a single-day sample detection capability of up to more than 500 people.
Cinema“The team’s inspection is efficient and fast, and the results are accurate, which greatly alleviates the pressure on our epidemic prevention and control sample testing. “Wuhan Center for Disease Control and Prevention highly praised this.
Fast response during wartime and orderly work are all thanks to Jiang Tao’s solid academic foundation and rich practical experience.
Cinema“Jiang Tao is a versatile player. “Academician Chen Wei, head of the military medical expert group, commented.
Jiang Tao has successively presided over and participated in the separation of pathogenic etiology such as SARS infection cases, H7N9 infection cases, and Babaylan card infection cases. He has participated in the development of dengue fever vaccines and SARS vaccines, and has established a pathogen isolation technology platform, nucleic acid detection technology platform and pathogenicity and transmission risk assessment platform for a series of infectious diseases, providing important technical support for the prevention and control of infectious diseases.
Respiratory infectious diseases have the characteristics of rapid transmission, wide coverage, and great harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing our army’s first emergency href=”https://comicmov.com/”>CinemaThe monitoring and early warning system for sexually transmitted respiratory infectious diseases has been constructed, and a series of technical specifications that have been presided over are used throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang Tao not only participated in the security tasks of a series of major domestic activities, but also went to Africa four times to perform medical treatment in Liberia, Sierra Leone and other countries. Treatment and rescue mission.
In 2015, in order to prevent and control the Ebola epidemic, Jiang Tao went to Sierra Leone with the mobile laboratory testing team to Serbia for the second time. The testing team led by him passed the World Health Organization’s laboratory parallel capability assessment with full scores.
In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test of an international organization. In the virus testing module, the team successfully and accurately in simulated samples filled with impurities. href=”https://comicmov.com/”>Cinema detected pathogens such as monkeypox virus and vaccinia virus, and accurately determined the strain to obtain excellent results.
Improving the accuracy of clinical diagnosis
In addition to carrying out the Cinema test work, Jiang Tao also used his professional expertise in the research field to lead the testing team to introduce other common respiratory infectious diseases in clinical samples.Carry out screening.
”In the suspected and confirmed cases of new coronavirus pneumonia, whether there are other respiratory virus infections or co-infections, this is of great reference value for precise prevention and control and clinical treatment.” Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said.
Exploring deep-seated virus transmission and pathogenic mechanisms is the key to defeating the epidemicBabaylan. Regarding the novel coronavirus detected in clinical samples, Jiang Tao led a team to continue to conduct sequencing analysis.
As the development of the virus epidemic, whether the genomic sequence has mutated, what are the characteristics of Komiks; in which regions and what are the impacts? Jiang Tao and his team are tirelessly studying and exploring.
In order to accelerate the effective integration of scientific research and clinical practice, Jiang Tao’s military medical expert group creatively used the diagnostic chain of viral nucleic acid detection, antibody detection, multiple pathogen detection, and whole genome sequencing to accurately diagnose new coronavirus infection or other pathogen infections in clinical patients, and applied it in the Optical Valley Campus of Hubei Province, Taikang Tongji Hospital, and other hospitals in Wuhan Taikang Tongji Hospital, effectively improving the accuracy of clinical diagnosis.
Forgot his family when he was ordered. After the epidemic is over, Jiang Tao plans to accompany his family. He and his wife agreed that when the epidemic is over, they will take their wife and children to Wuhan again to see how everything looks after it returns to normal, and to see the Wuhan Yangtze River Bridge and Yellow Crane Tower, and to talk about their experience in fighting the epidemic in Wuhan.
The epidemic is immortal and the charge continues. This is the warrior Jiang CinemaTao.