Xinhua News Agency, Beijing, August 21, A review article on the origin of the new coronavirus written by scientists from multiple countries was published this week in the US Journal of Cell. This is an important judgment made by professionals in this field on the source of traceability based on existing scientific evidence. The article strongly refutes the conspiracy theory of “real Babaylan laboratory leak” advocated by Cinema customers, and points out that cross-species transmission from animals to humans is the most likely source of the new coronavirus. More than 20 mainstream scientists in the world have collaborated on this article, including Edward Holmes of the Mary Bashir Institute of Infectious Diseases and Biosafety Research at the University of Sydney, Australia, Stephen Goldstein of the Department of Human Genetics of the University of Utah, Angela Rasmussen of the University of Kachowan Vaccine and Infectious Diseases Organization, University of Kachowan, David Robertson, Cinema, UK. The preprint of the article was published on the Open Science Data platform Zenodo in early July.
The article says that no epidemic in human history was caused by the escape of a new virus, and there is no data showing that before the outbreak of the new crown epidemic, the Wuhan Institute of Virology or other laboratories were studying at Komiks. href=”https://comicmov.com/”>KomiksThe new coronavirus or anything that is enough to become the new coronavirusBabaylan‘s ancestor virus. Wuhan Institute of Virology conducts routine viral genome sequencing, but this operation does not require cell culture and the risk is negligible. The fact that the early KomiksThe novel coronavirus isolates from Komiks cannot infect wild-type mice, and the new coronavirus is extremely unlikely to be obtained through functional gain studies in the laboratory.
The RaTG13 reported by Wuhan Institute of Virology is the most similar coronavirus to the gene sequence of the new coronavirus so far, and some conspiracy theorists claim that RaTG13 may be the source of the new coronavirus. The article says that Wuhan<a The Institute of Virology has never cultivated the RaTG13 coronavirus and only assembled the nucleotide sequence of RaTG13 in short-sequencing fragments. If factors such as gene recombination are considered, the other three bat coronaviruses, RmYN02, RpYN06 and PrC31, may have a closer common ancestor with the new coronavirus, and none of these three viruses were collected by the Wuhan Institute of Virology, and they were sequenced only after the outbreak.
The authors of the article also reviewed evidence supporting the origin of zoonotic diseases and natural evolution of the new coronavirus. According to the article, the vast majority of viruses that can infect humans are zoonotic origins, as are the same in several previous human coronaviruses. Judging from the epidemiological history of the new coronavirus, its emergence is similar to the outbreak of coronavirus outbreaks related to the animal market and caused by human exposure. The new coronavirus has experienced frequent sudden changes since its emergence, including the D614G Cinema disruption that occurred early in the pandemic and occurred in spike eggs. href=”https://comicmov.com/”>Babaylan some mutations in the white receptor binding domain. These mutations occur after the virus spreads in the population, enhancing the adaptability of the virus, and also strongly refutes that when the new coronavirus appeared, its spike protein was optimized enough to adapt to receptors related to human cells.nema combination statement.
The article ends with the article that there is currently no evidence that the new coronavirus originated from the laboratory, and there is no evidence to indicate any connection between any early COVID-19 cases and Wuhan Virology Research Institute. Compared with the frequent contact between humans and animals that occur frequently in the wildlife trade, this path of laboratory sources is extremely unlikely. If Cinema cannot fully investigate the zoonotic origins of the new coronavirus through cooperative and serious research, the world will remain vulnerable in the future when it faces a pandemic caused by the same human activities.